Decompression and internal fusion were performed for 3 patients w

Decompression and internal fusion were performed for 3 patients with aneurysmal bone cysts. Of the 23 patients, 7 underwent dorsal fusion and 4 underwent ventral fusion of the axis body. Chemotherapy was necessary for the patients with eosinophilic granuloma with multifocal disease and for the patient with Ewing’s sarcoma. There was no morbidity, and there were no deaths. All patients with benign lesions were free of disease at the time of the follow-up visit (mean +/- SD follow-up 8.8 +/- 1.1 years; range 2-18 years). Chordomas received proton or LINAC irradiation, and as of 4-15 years of follow-up, no recurrence has been noted.

Conclusions.

Because most atlantoaxial tumors in children are GANT61 solubility dmso benign, an intralesional procedure could suffice. Vascular control and staged resection are critical. Ventral transoral fusion or lateral extrapharyngeal GW786034 clinical trial fusion has been successful. Resection with ventral fusion and reconstruction are essential for vertebral body collapse. Management of eosinophilic granulomas must be individualized and might require diagnosis through needle biopsy.”
“Herbs have been a huge source of natural substances used to treat and prevent several illnesses; therefore it is vital to identify the probable toxicity that might take place as a consequence of using herbal combinations.

This study was undertaken in rabbits to investigate the

hepatoprotective effects of herbal drug in normal and CCl4-induced hepatic damage. Herbal drug was tested in 3 different doses, each group comprising of seven rabbits of either sex followed by the administration selleck chemicals llc of CCl4 with herbal drug and saline for 45 days. Liver function tests and histopathological evaluation were carried out at the end of dosing using standards kits.

The result shows that normal dose of herbal drug (0.43 ml/kg) possess hepatoprotective effects against CCl4 induced liver damage in rabbits which

may be due to the various active ingredients present in herbal drug combination. Present study also suggests that there was a significant (P<0.05) increase in serum alkaline phosphatase and gamma-GT in animals kept on high dose of herbal drug (10 ml/kg); however studies on huge number of animals and humans are requisite before reaching to definite conclusion.”
“Stem cell transplantation is a promising new therapeutic option in different neurological diseases. However, it was not yet possible to translate its potential from animal models to clinical application. One of the main problems of applying stem cell transplantation in clinical medium is the difficulty of detection, localization, and examination of the stem cells in vivo at both cellular and molecular levels. State-of-the-art molecular imaging techniques provide new and better means for noninvasive, repeated, and quantitative tracking of stem cell implant or transplant.

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