The results suggested that the overall cure time decreased with OBSH and ADC contents. The OBSH was more effective in cure-acceleration of the NR/SBR blend than the ADC. The NR/SBR vulcanized foams produced by OBSH and GDC-0973 purchase ADC agents had closed-cell structures. The specific density and mechanical properties of the blend tended to decrease with increasing blowing agent content. The CB gave NR/SBR foams with smaller cell size, better cell dispersion, and higher mechanical properties than the precipitated silica

and FA particles. The heat ageing and weathering resulted in an increase in tensile modulus and hardness, but lowered the tensile strength, ultimate elongation and tear strength. The selleck kinase inhibitor elastic recovery for cellular NR/SBR vulcanizates with FA was superior to that with CB and silica, the elastic recovery of the blends decreasing with blowing agent content. Resilience property was improved by the presence of gas phases. The optimum concentration of OBSH and ADC to be used for NR/SBR vulcanizates was 4 phr. (C) 2009 Wiley Periodicals, Inc. J Appl Polym Sci 114: 2816-2827, 2009″
“Background-High levels of cardiac troponin T, measured by a highly sensitive assay (hs-cTnT), are strongly associated with incident coronary heart disease and heart failure. To date, no large-scale genome-wide association study of hs-cTnT has been reported. We

sought to identify novel genetic variants that are associated with hs-cTnT levels.

Methods

and Results-We performed a genome-wide association in 9491 European Americans and 2053 blacks free of coronary heart disease and heart failure CA3 concentration from 2 prospective cohorts: the Atherosclerosis Risk in Communities Study and the Cardiovascular Health Study. Genome-wide association studies were conducted in each study and race stratum. Fixed-effect meta-analyses combined the results of linear regression from 2 cohorts within each race stratum and then across race strata to produce overall estimates and probability values. The meta-analysis identified a significant association at chromosome 8q13 (rs10091374; P=9.06×10(-9)) near the nuclear receptor coactivator 2 (NCOA2) gene. Overexpression of NCOA2 can be detected in myoblasts. An additional analysis using logistic regression and the clinically motivated 99th percentile cut point detected a significant association at 1q32 (rs12564445; P=4.73×10(-8)) in the gene TNNT2, which encodes the cardiac troponin T protein itself. The hs-cTnT-associated single-nucleotide polymorphisms were not associated with coronary heart disease in a large case-control study, but rs12564445 was significantly associated with incident heart failure in Atherosclerosis Risk in Communities Study European Americans (hazard ratio=1.16; P=0.004).