The solubility of GLY in oils, cosurfactants, and surfactants was evaluated to identify the components of the microemulsion. The ternary diagram was plotted to identify the area of microemulsion existence. The in vitro dissolution pro. le of GLY SMEDDS was evaluated in comparison to the marketed GLY tablet and pure drug in pH 1.2 and pH 7.4 buffers. The chemical stability of GLY in SMEDDS was determined as per the International Conference on Harmonisation
guidelines. The area of microemulsion existence increased with the increase in the cosurfactant (Transcutol P) concentration. The GLY microemulsion exhibited globule size of 133.5 nm and polydispersity index of 0.94. The stability studies indicated that GLY undergoes significant degradation in the developed SMEDDS. This observation was totally selleck chemical unexpected and has been noticed for the first time. Further
investigations indicated that the rate of GLY degradation was highest in Transcutol P.”
“Wan-chak-motluk is a Thai local name for native species of Curcuma (Zingiberaceae) that produce phytoestrogen in their rhizomes. Wan-chak-motluk has long been used in Thai traditional medicine for treatment of illness in the uterus and ovarian hormone deficit, and therefore it is cultivated for economic purposes throughout Thailand. this website The rhizome morphology of wan-chak-motluk is highly variable and this may be
related to its medicinal properties. Thus, this study aimed to identify and classify wan-chak-motluk collected from cultivation sites in 16 provinces of Thailand. Chromosome numbers, together with inflorescent, floral, and leaf morphology, were used to separate wan-chak-motluk into five cultivars belonging to three species: C. comosa, C. elata, and C. latifolia. Curcuma comosa has short (2-5 cm) peduncle, glabrous lower leaf, and consists of two cultivars. One cultivar has a cylindrical spike 13-17 cm long and 5-8 cm wide, whereas the cylindrical spike of the other cultivar is shorter (10-15 cm) but larger (8-12 cm). The former cultivar has 2n = 42 and find more the latter has 2n = 63, seldom 2n = 62 or 64. Both C. elata and C. latifolia have long (10-25 cm) peduncle and pubescent lower leaf. They differ in that C. latifolia has 2n = 63 and 84 with a red path along the midrib, whereas C. elata has 2n = 63 without a red path along the midrib. This study shows that chromosome numbers can be used to accurately verify the taxonomic identification of wan-chak-motluk.”
“Japanese encephalitis virus (JEV) causes serious zoonosis in South Asia, Southeast Asia and other areas. Pigs are an important reservoir for this virus in nature. The treatment of JEV infection in pigs is important for controlling the prevalence of JEV in humans and economic losses in pig farming.