However, COX-2 induced by LPS
was not significantly altered by the Corni fructus extract. The Corni fructus extract contains anti-oxidant components including phenolics, flavonoids and anthocyanin at the concentration of 18.07, 2.31 and 7.83 mg/g, respectively. The subsequent chloroform fraction enriched with flavonoids almost completely blocked the iNOS induction and NO production Caspase inhibitor caused by LPS in the Raw cells.”
“Linear (1-arm) and star-shaped (4-, 6-, and 16-arm) poly(D,L-lactide)s (PDLLs) were synthesized by ring-opening polymerization in bulk of D,L-lactide monomer. Hydroxyl end-group compounds and stannous octoate were used as the initiator and catalyst, respectively. The intrinsic https://www.selleckchem.com/products/kpt-8602.html viscosity and glass transition temperature (Tg) of the PDLLs decreased steadily as the branch arm number increased for similar molecular weights. However,
the intrinsic viscosity and Tg values of the linear PDLL were less than the star-shaped PDLL for similar each PDLL arm lengths. Ibuprofen, a poorly water soluble model drug was entrapped in the PDLL microspheres. All drug-loaded PDLL microspheres were prepared by the oil-in-water emulsion solvent evaporation method, were spherical in shape, and had a smooth surface with fine dispersibility. In vitro drug release behaviors indicated that the drug release from the microspheres with higher branch arm number was faster than from those with lower branch arm 3-deazaneplanocin A number. Moreover, the drug release from the star-shaped PDLL microspheres was
slower than that of the linear PDLL microspheres for similar PDLL arm lengths. The drug release behavior could be adjusted through both the branch arm number and arm length of PDLL. (C) 2011 Wiley Periodicals, Inc. J Appl Polym Sci, 2012″
“Lattice dynamics, low-temperature electrical transport, and high-temperature thermoelectric properties of (In, Yb)-doped CoSb3 thin films on different substrates are reported. Pulsed laser deposition under optimized conditions yielded single-phase polycrystalline skutterudite films. Raman spectroscopy studies suggested that In and Yb dopants occupy the cage sites in the skutterudite lattice. Low-temperature electrical transport studies revealed the n-type semiconducting nature of the films with extrinsic and intrinsic conduction mechanisms, in sharp contrast to the degenerate nature reported for identical bulk samples. Calculations yielded a direct bandgap close to 50 meV with no evidence of an indirect gap. The carrier concentration of the films was identical to that reported for the bulk and increased with temperature beyond 250 K. The higher resistivity exhibited is attributed to the enhanced grain boundary scattering in films with a high concentration of grains. The maximum power factor of similar to 0.