Comparison with YFe2H4.2 and YFe2D4.2 compounds shows that the temperature at which appears the second transition is shifted to lower values. The transition field increases linearly versus temperature but with a much larger Delta H-TR/Delta T slope for the deuteride compared to the hydride whereas there were similar in the nonsubstituted compounds. The roles of both cell volume change and erbium magnetic contribution are briefly discussed. (C) 2010 American Institute of Physics. [doi:10.1063/1.3360346]“
“Background and Aim: Recent evidence suggests that genistein aglycone may act beneficially on surrogate cardiovascular

risk markers in postmenopausal women. We assessed the effects of genistein aglycone on some cardiovascular risk factors and homocysteine levels after 3-years of continued therapy in a cohort of osteopenic, 3-MA cell line postmenopausal women.

Methods and Results: The parent study was a randomized, double-blind, placebo-controlled trial involving 389 postmenopausal women with low bone mass for 24 months. Subsequently, a subcohort (138 patients) continued therapy for an additional year. Participants received 54 mg of genistein aglycone (n = 71) or placebo (n = 67), daily. Both arms received calcium

and vitamin D(3) in therapeutic doses. Moreover, 4 weeks before randomization procedures and during our follow-up study, all patients received dietary instructions in an isocaloric fat-restricted Staurosporine mw diet. Blood lipid profiles, fasting glucose and insulin, insulin resistance (HOMA-IR), fibrinogen, osteoprotegerin (OPG)

and homocysteine at baseline and after 24 and 36 months of treatment were measured.

Compared to placebo, genistein significantly decreased fasting glucose and insulin, HOMA-IR, fibrinogen and homocysteine after 24 and 36 months of treatment. By contrast, isoflavone administration did not affect high-density lipoprotein cholesterol and triglycerides though serum OPG was higher in the genistein recipients. There were no differences in adverse events or discomfort selleck between groups. Results on routine biochemical, liver function, and hematologic testing did not change over time in placebo or genistein group.

Conclusions: After 3-years of treatment, genistein aglycone plus calcium, vitamin D(3) and a healthy diet showed positive effects on some cardiovascular risk factors and homocysteine levels in a cohort of postmenopausal women with low bone mass. (C) 2009 Elsevier B.V. All rights reserved.”
“The adsorption of penicillin G acylase (PGA) from B. megaterium and from Escherichia coli on a cationic resin, Streamline SP XL, was studied using both packed and expanded beds. Stability assays showed that penicillin acylases from the two sources presented high irreversible deactivation at pH 4.0 and 4.5, but remained stable at pH 4.8. Adsorption experiments performed in a packed bed (PB), in the pH range 4.8-5.8, showed highest adsorption yields at pH 4.8, for both enzymes.