This was a retrospective clinical analysis
of 89 patients who underwent hysteroscopic adhesiolysis by monopolar electrode knife. A second-look office hysteroscopy was performed in all cases after 2 months. On second-look hysteroscopy, 12 patients showed reformation of adhesions and needed a repeat procedure.
The mean age of the patient was 28.4 years. In the majority (64%) of patients, the possible cause of Asherman’s syndrome SB525334 TGF-beta/Smad inhibitor was previous curettage on gravid uterus. The overall conception rate was 40.4% after hysteroscopic adhesiolysis. The mean conception time after surgery was 12.8 months. There was no conception in patients who needed repeat adhesiolysis. The conception rate was higher (58%) in mild Asherman’s syndrome compared to 30% conception rate in moderate and 33.3% conception rate in severe cases. There was no significant association between conception rate and preoperative menstrual pattern. There was significant higher likelihood
of conception rate (44.3%) in those who continued to have improved menstrual pattern compared to only 10% likelihood of conception in those who continued to have amenorrhea after adhesiolysis. The live birth rate was 86.1% and miscarriage rate was 11.1%. Cumulative pregnancy rate showed that 97.2% patients conceived within 24 months. There was increased incidence (43.8%) of cesarean section. Four (12.5%) patients had postpartum hemorrhage for adherent placenta.
Hysteroscopic adhesiolysis for Asherman’s syndrome Selleckchem ATM inhibitor is a safe and effective method of choice for restoring menstrual function Givinostat in vitro and fertility.”
“To
study the efficacy and safety of performing anterior mesh (Perigee) with vaginal reconstructive surgeries (sacrospinous ligament fixation) for treatment of advanced prolapse.
One hundred twenty-eight patients, POP-Q stage III (n = 85) or IV (n = 43), underwent surgery. The objective cure was defined as less than stage 2 prolapse. Introital ultrasonography was used for mesh morphological evaluation.
Post-operative data were available for 120 patients. At 30 months, the objective cure was 91.8%. The subjective cure was 93.3% on POPDI-6 feedback. No apical and anterior recurrence was observed. Surgical complications were minor. Five cases (4.1%) of mesh extrusion was observed. Mesh shortening, shrinkage, and thickening was also observed.
The combination of anterior vaginal mesh and vaginal reconstructive surgery appears to be a safe and effective in restoring the anatomy and achieving favorable pelvic function. The anterior mesh deployed seems to cover a lesser area than anticipated. A longer period of follow-up is necessary to confirm its efficacy.”
“Study Design. In vitro human cadaveric biomechanical study.
Objective. This study quantifies the multidirectional flexibility of the spine following laminoplasty and laminectomy after cervical disc arthroplasty.
Summary of Background Data.