6 million adults) have access to the Internet (Office for Nationa

6 million adults) have access to the Internet (Office for National Statistics 2013a), and 73 % (36 million) adults access the Internet every day (Office for National Statistics 2013b). Worldwide, 34 % of the population have access to the Internet, with usage least in Africa and Selleck CHIR99021 highest in North America (Internet World Stats 2012). Social networking sites are used by 72 % of adults who are online (Brenner and Smith 2013). The age group of users that has seen the most significant growth has been amongst the over 65 s, with their presence tripling over the last 4 years from 13 % in 2009 to 43 % in 2013 (Brenner and Smith

2013). Thus, the Internet provides access to a worldwide convenience sample for any sort of research. By its very nature, enabling electronic connections to be made between users means it is also ripe for snowball learn more sampling. It is for these reasons that we chose this as our medium for delivery of the survey.   2. Social networking Signposting potential research participants to the survey could be done via any number of strategies, and before recruitment started it was not possible to predict which method would be the Dinaciclib cell line most successful. As there are many social networking sites

frequented by candidate research participants the decision was made to use an eclectic mix of the most popular sites: Facebook, Twitter and LinkedIn. A thorough review of what is available in terms of social media can be found in the following comprehensive text, ‘Blogging and other social media’ (Newson et al. 2008). 1. Facebook was founded in 2004

by Mark Zuckerberg; it is a website that allows users to keep in touch with their friends, and people use it to share life events, photos and post messages. As of June 2013, it had 1.15 billion active users worldwide (Facebook 2013). Facebook connects people who have a personal or professional interest in genetics (e.g. American Society Human Genetics https://​www.​facebook.​com/​GeneticsSociety) but can also connect people who may have no specialist knowledge of genetics but just enjoy engaging in debate about interesting scientific issues (e.g. The Naked Scientists https://​www.​facebook.​com/​thenakedscientis​ts). Searching for groups or individuals PLEKHB2 interested in genetics or genomics reveals millions of hits.   2. Twitter was created in 2006. It is a website that enables users to send ‘tweets’ or text messages that contain 140 characters or less. As of September 2013, Twitter had 200 million users sending 400 million daily tweets (TECHi 2013). Daily conversations that cover issues relating to genetics are prolific; almost every permutation of discussion is possible, e.g. genomic researchers discussing the latest sequencing platforms search Twitter using #NGS, through to members of the public exploring a genetic diagnosis, see #geneticcondition.   3. LinkedIn is a networking site for professionals.

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