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Ilomastat chemical structure pigs identical to isolates from affected humans. Environ Microbiol 2009, 11:505–511.PubMedCrossRef 5. He M, Sebaihia M, Lawley TD, Stabler RA, Dawson LF, Martin MJ, et al.: Evolutionary dynamics of Clostridium difficile over short and long time scales. Proc Natl Acad Sci USA 2010, 107:7527–7532.PubMedCrossRef 6. Stabler RA, He M, Dawson L, Martin M, Valiente

E, Corton C, et al.: Comparative genome and phenotypic analysis of Clostridium difficile 027 strains provides insight into the evolution of a hypervirulent bacterium. Genome Biol 2009, 10:R102.PubMedCrossRef 7. Sebaihia M, Wren BW, Mullany P, Fairweather NF, Minton N, Stabler R, et al.: The multidrug-resistant human pathogen Clostridium difficile has a highly mobile, mosaic genome. Nat Genet 2006, 38:779–786.PubMedCrossRef 8. Forgetta V, Oughton MT, Marquis P, Brukner I, Blanchette R, Haub K, et al.: Fourteen-Genome Comparison Identifies DNA Markers for Severe-Disease-Associated Strains selleck kinase inhibitor of Clostridium difficile. J Clin Microbiol 2011, 49:2230–2238.PubMedCrossRef 9. Marsden GL, Davis IJ, Wright VJ, Sebaihia M, Kuijper EJ, Minton NP: Array see more comparative hybridisation reveals a high degree of similarity between UK and European clinical isolates of hypervirulent Clostridium difficile. BMC Genomics 2010, 11:389.PubMedCrossRef 10. Stabler RA, Gerding DN, Songer

JG, Drudy D, Brazier JS, Trinh HT, et al.: Comparative phylogenomics of Clostridium difficile reveals clade specificity and microevolution of hypervirulent strains. J Bacteriol 2006, 188:7297–7305.PubMedCrossRef 11. {Selleck Anti-infection Compound Library|Selleck Antiinfection Compound Library|Selleck Anti-infection Compound Library|Selleck Antiinfection Compound Library|Selleckchem Anti-infection Compound Library|Selleckchem Antiinfection Compound Library|Selleckchem Anti-infection Compound Library|Selleckchem Antiinfection Compound Library|Anti-infection Compound Library|Antiinfection Compound Library|Anti-infection Compound Library|Antiinfection Compound Library|Anti-infection Compound Library|Antiinfection Compound Library|Anti-infection Compound Library|Antiinfection Compound Library|Anti-infection Compound Library|Antiinfection Compound Library|Anti-infection Compound Library|Antiinfection Compound Library|Anti-infection Compound Library|Antiinfection Compound Library|Anti-infection Compound Library|Antiinfection Compound Library|Anti-infection Compound Library|Antiinfection Compound Library|buy Anti-infection Compound Library|Anti-infection Compound Library ic50|Anti-infection Compound Library price|Anti-infection Compound Library cost|Anti-infection Compound Library solubility dmso|Anti-infection Compound Library purchase|Anti-infection Compound Library manufacturer|Anti-infection Compound Library research buy|Anti-infection Compound Library order|Anti-infection Compound Library mouse|Anti-infection Compound Library chemical structure|Anti-infection Compound Library mw|Anti-infection Compound Library molecular weight|Anti-infection Compound Library datasheet|Anti-infection Compound Library supplier|Anti-infection Compound Library in vitro|Anti-infection Compound Library cell line|Anti-infection Compound Library concentration|Anti-infection Compound Library nmr|Anti-infection Compound Library in vivo|Anti-infection Compound Library clinical trial|Anti-infection Compound Library cell assay|Anti-infection Compound Library screening|Anti-infection Compound Library high throughput|buy Antiinfection Compound Library|Antiinfection Compound Library ic50|Antiinfection Compound Library price|Antiinfection Compound Library cost|Antiinfection Compound Library solubility dmso|Antiinfection Compound Library purchase|Antiinfection Compound Library manufacturer|Antiinfection Compound Library research buy|Antiinfection Compound Library order|Antiinfection Compound Library chemical structure|Antiinfection Compound Library datasheet|Antiinfection Compound Library supplier|Antiinfection Compound Library in vitro|Antiinfection Compound Library cell line|Antiinfection Compound Library concentration|Antiinfection Compound Library clinical trial|Antiinfection Compound Library cell assay|Antiinfection Compound Library screening|Antiinfection Compound Library high throughput|Anti-infection Compound high throughput screening| Brouwer MSM, Warburton PJ, Roberts AP, Mullany P, Allan E: Genetic Organisation, Mobility and Predicted Functions of Genes on Integrated, Mobile Genetic Elements in Sequenced Strains of Clostridium difficile. PLoS One 2011, 6:e23014.PubMedCrossRef 12. Tan KS, Wee BY, Song KP: Evidence for holin function of tcdE gene in the pathogenicity of Clostridium difficile. J Med Microbiol 2001, 50:613–619.PubMed 13. Braun V, Hundsberger T, Leukel P, Sauerborn M, von Eichel-Streiber C: Definition of the single integration site of the pathogenicity locus in Clostridium difficile. Gene 1996, 181:29–38.PubMedCrossRef 14. Govind R, Vediyappan G, Rolfe RD, Dupuy B, Fralick JA: Bacteriophage-mediated toxin gene regulation in Clostridium difficile. J Virol 2009, 83:12037–12045.PubMedCrossRef 15.